Journal of Emergencies, Trauma, and Shock
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EVIDENCE BASED REVIEW
Year : 2009  |  Volume : 2  |  Issue : 1  |  Page : 3-5

Use of antiemetics in children with acute gastroenteritis: Are they safe and effective?


Henry Ford Hospital, 2799 W. Grand Blvd, Detroit, MI 48201, USA

Correspondence Address:
Jacob Manteuffel
Henry Ford Hospital, 2799 W. Grand Blvd, Detroit, MI 48201
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-2700.44674

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The use of antiemetics is a controversial topic in treatment of pediatric gastroenteritis. Although not recommended by the American Academy of Pediatrics, antiemetics are commonly prescribed by physicians. A review of the literature shows side effects of promethazine, prochlorperazine, and metoclopramide are common and potentially dangerous. Ondansetron has recently been studied as an adjunct to oral rehydration therapy in treatment of acute gastroenteritis with mild to moderate dehydration. Although studies are limited, early research suggests the medication is safe when used in a single dose and can be effective to prevent vomiting, the need for intravenous fluids, and hospital admission.


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